Toxicology, Physiology and Molecular Mechanisms【毒理学、生理学和分子机制】
Chronic diseases such as COPD, asthma, cancer, pulmonary fibrosis, and cardiovascular diseases are major causes of morbidity and mortality, and environmental exposures are the key drivers of these diseases. Research in the Toxicology, Physiology and Molecular Mechanisms (TPMM) track is focused on discovering novel molecular mechanisms that drive the pathophysiology of major chronic diseases, with the goal of developing prevention and therapeutic strategies to improve public health. The track is supported by NIEHS and NHLBI research training grants.Students in this track will engage in academic training in specific areas of environmental health with in-depth courses in molecular, toxicologic, physiologic, immunologic, and pathophysiologic sciences. Prior to focusing on a specific area of thesis research, they will also obtain a broad background in environmental health sciences by taking core courses that underlie its scientific basis. During the first year, students will begin to engage in research by doing lab rotations with selected faculty. Training in writing scientific papers and grant proposals is also included in the curriculum.
The research done by PhD students, postdoctoral fellows, and faculty has led directly to an enhanced understanding of the biological changes that represent the early stages and progression of many chronic diseases. The track is aimed towards creating the next generation of scientists with laboratory skills to tackle complex environmental effects in individuals and in the population. Graduates can look forward to successful careers in academic or industrial research and government or regulatory agencies.
慢性阻塞性肺病、哮喘、癌症、肺纤维化和心血管疾病等慢性疾病是发病和死亡的主要原因，而环境暴露是这些疾病的主要驱动因素。毒理学、生理学和分子机制 (TPMM) 方向的研究重点是发现驱动主要慢性疾病病理生理学的新型分子机制，目的是制定预防和治疗策略以改善公共卫生。学生将参加环境健康特定领域的学术培训，并深入学习分子、毒理学、生理学、免疫学和病理生理学科学课程。在专注于特定论文研究领域之前，他们还将通过学习作为其科学基础的核心课程，获得环境健康科学的广泛背景。博士生、博士后研究员和教员所做的研究直接促进了人们对许多慢性疾病早期阶段和发展过程中的生物变化的理解。
该方向旨在培养具有实验室技能的下一代科学家，以解决个人和人群中复杂的环境影响。毕业生可以期待在学术或工业研究以及政府或监管机构中获得成功的职业生涯。
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- 从业年限
- 15年
- 帮助人数
- 50人
- 平均响应
- 15分钟内
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