| 2016 | 2015 | Institution | Country | Academic | Employer | Citations | H | Score |
| 1 | 1 | Harvard University | United States | 96.4 | 99.3 | 94.7 | 100.0 | 97.2 |
| 2 | 2 | University of Cambridge | United Kingdom | 95.4 | 100.0 | 92.1 | 90.0 | 93.7 |
| 3 | 4 | Massachusetts Institute of Technology (MIT) | United States | 90.1 | 94.5 | 100.0 | 90.2 | 93.0 |
| 4 | 3 | University of Oxford | United Kingdom | 94.1 | 98.7 | 89.9 | 88.4 | 92.1 |
| 5 | 5 | Stanford University | United States | 90.4 | 91.9 | 92.2 | 90.6 | 91.1 |
| 6 | 7 | University of California, Berkeley (UCB) | United States | 90.5 | 89.5 | 93.9 | 80.5 | 88.8 |
| 7 | 6 | California Institute of Technology (Caltech) | United States | 100.0 | 72.5 | 94.4 | 69.1 | 88.1 |
| 8 | 9 | Yale University | United States | 85.4 | 88.3 | 89.3 | 83.5 | 86.2 |
| 9 | 10 | ETH Zurich (Swiss Federal Institute of Technology) | Switzerland | 96.0 | 83.9 | 84.3 | 71.4 | 85.7 |
| 10 | 11 | University of California, Los Angeles (UCLA) | United States | 83.1 | 84.6 | 88.3 | 84.7 | 85.0 |
| 11 | 14 | University of California, San Diego (UCSD) | United States | 81.9 | 73.6 | 91.4 | 86.9 | 84.7 |
| 12 | 16 | Kyoto University | Japan | 91.9 | 89.1 | 81.3 | 71.7 | 83.9 |
| 13 | 12= | University of California, San Francisco (UCSF) | United States | 79.4 | 62.6 | 93.9 | 88.5 | 83.6 |
| 14 | 17= | University of Toronto | Canada | 77.2 | 88.5 | 86.7 | 87.2 | 83.2 |
| 15 | 8 | National University of Singapore (NUS) | Singapore | 84.7 | 91.6 | 83.5 | 76.3 | 83.0 |
| 16= | 12= | Cornell University | United States | 79.6 | 83.0 | 87.7 | 82.0 | 82.6 |
| 16= | 15 | Imperial College London | United Kingdom | 83.9 | 88.5 | 82.6 | 78.0 | 82.6 |
| 18 | 19 | Princeton University | United States | 87.9 | 82.8 | 89.8 | 66.0 | 82.4 |
| 19 | 17= | UCL (University College London) | United Kingdom | 79.7 | 85.3 | 83.2 | 83.3 | 82.0 |
| 20 | 20= | Columbia University | United States | 77.5 | 82.7 | 89.1 | 81.6 | 81.9 |
| 21 | 31= | Rockefeller University | United States | 78.4 | 60.9 | 99.3 | 77.9 | 81.8 |
| 22 | 20= | The University of Tokyo | Japan | 85.9 | 89.4 | 79.3 | 71.7 | 81.1 |
| 23 | 25 | Duke University | United States | 74.4 | 82.0 | 89.5 | 82.2 | 80.9 |
| 24 | 24 | University of Washington | United States | 74.4 | 71.9 | 88.2 | 86.1 | 80.5 |
| 25 | 22= | University of Edinburgh | United Kingdom | 78.9 | 74.3 | 85.9 | 79.1 | 80.2 |
| 26 | 29= | University of Chicago | United States | 78.7 | 69.3 | 88.4 | 78.0 | 80.0 |
| 27 | 27 | The University of Melbourne | Australia | 78.8 | 87.2 | 81.6 | 76.7 | 79.8 |
| 28 | 22= | Johns Hopkins University | United States | 69.8 | 77.3 | 87.4 | 88.9 | 79.7 |
| 29 | 26 | University of Pennsylvania | United States | 68.7 | 81.8 | 89.5 | 86.1 | 79.6 |
| 30 | 38 | Osaka University | Japan | 79.0 | 82.9 | 84.4 | 73.4 | 79.3 |
| 31 | 29= | University of California, Davis (UCD) | United States | 82.5 | 70.2 | 82.3 | 73.6 | 79.0 |
| 32= | 31= | University of Michigan | United States | 67.6 | 78.4 | 87.8 | 86.0 | 78.3 |
| 32= | 34= | Washington University in St. Louis | United States | 69.5 | 64.4 | 90.8 | 85.3 | 78.3 |
| 34 | 28 | Ludwig-Maximilians-Universität München | Germany | 72.6 | 77.8 | 83.7 | 81.6 | 78.1 |
| 35 | 39 | University of British Columbia | Canada | 76.1 | 80.1 | 82.2 | 73.3 | 77.3 |
| 36 | 43 | Australian National University (ANU) | Australia | 85.4 | 84.3 | 81.1 | 57.1 | 77.1 |
| 37 | 34= | McGill University | Canada | 74.1 | 81.3 | 81.6 | 75.2 | 77.0 |
| 38= | 46 | Ecole Polytechnique Fédérale de Lausanne (EPFL) | Switzerland | 70.8 | 80.4 | 94.3 | 67.7 | 76.9 |
| 38= | 36 | University of Copenhagen | Denmark | 69.8 | 79.1 | 83.5 | 80.7 | 76.9 |
| 40 | 40 | Karolinska Institute | Sweden | 66.0 | 86.4 | 85.0 | 81.7 | 76.7 |
| 41 | 37 | The University of Queensland (UQ) | Australia | 73.8 | 82.9 | 80.1 | 74.9 | 76.6 |
| 42 | 44= | Ruprecht-Karls-Universität Heidelberg | Germany | 73.1 | 69.6 | 84.2 | 74.7 | 75.9 |
| 43 | 47 | Uppsala University | Sweden | 75.6 | 71.9 | 81.7 | 71.5 | 75.7 |
| 44 | 33 | University of Wisconsin-Madison | United States | 71.4 | 65.6 | 85.5 | 76.3 | 75.6 |
| 45 | 50 | New York University (NYU) | United States | 64.9 | 74.8 | 89.2 | 78.6 | 75.4 |
| 46 | 49 | The University of Manchester | United Kingdom | 72.2 | 69.5 | 83.5 | 74.1 | 75.2 |
| 47 | 41 | Technische Universität München | Germany | 70.7 | 71.1 | 83.5 | 73.9 | 74.7 |
| 48 | 51-100 | Peking University | China | 75.1 | 87.7 | 75.9 | 67.3 | 74.6 |
| 49= | 44= | King's College London (KCL) | United Kingdom | 60.6 | 77.9 | 87.0 | 81.1 | 74.1 |
| 49= | 51-100 | University of Hong Kong (HKU) | Hong Kong | 73.6 | 88.9 | 79.9 | 63.0 | 74.1 |
